Biossance Squalane + Copper Peptide Serum: My Review After 2.5 Months

My verdict up front

I have been using the Biossance Squalane + Copper Peptide Rapid Plumping Serum for over two and a half months now, twice daily, morning and night. I am about halfway through the bottle. Of the copper peptide serums I have personally used, this is the one that felt the most premium, and it is the one I noticed the most from. Based on my own experience, it earns a 4.5 out of 5. The main catch is the price.

Those are my actual bottles, part of the Biossance squalane range I have been using. Everything below is my firsthand experience, and the usual caveat applies: one person’s skin is one data point, not a guarantee.

How I used it

Twice a day, morning and night, applied to my face, over about two and a half months of consistent use. I want to be upfront that consistency is the whole thing here. The results I describe below came from using it every day, not from occasional use.

What I actually noticed

Right away: plumpness and hydration. This was the immediate effect for me. From the early uses my skin felt plumper and more hydrated. The squalane base likely helps here, it is a hydrating carrier, and the “rapid plumping” name matched what I felt.

After three to four weeks: smoother texture. A few weeks in, I noticed my overall skin texture felt smoother. Not dramatic overnight, but a real change I could feel by the one-month mark.

Around six weeks: the look of fine lines. After about a month and a half, I personally noticed the look of my finer lines soften. I want to be careful with this one: this is my own observation over time, not a promise that it will reduce anyone’s wrinkles. Skin varies, and copper peptides are a slow, cumulative ingredient.

Feel and finish. This is where it stood out to me. It feels premium compared to others I have used. No aeration issues, no bad smell, and it leaves my skin feeling healthy and radiant rather than greasy or coated.

The honest caveat

A few things to weigh. First, price: this sits at the premium end, around $69, versus something like The Ordinary near $32. You are paying for the squalane formulation and the finish, and for me it was worth it, but it is a real step up in cost. Second, the squalane base is oil-adjacent, so it may suit normal-to-dry skin better than very oily skin. It worked well for me, but if you are very oily you might prefer a lighter, water-based option.

Third, and I have to be straight about this because label transparency is the whole point of this site: Biossance does not disclose how much copper peptide is actually in the formula. My 4.5 is based on how it performed and felt for me over two and a half months, not on a known concentration, because there is not a published one. If a stated dose is what you care about, a serum like MAXXING or NIOD prints the number and Biossance does not. I break down why that gap matters in what “1% copper peptides” actually means.

How it compares

If you want the cheapest way to try copper peptides, The Ordinary is the entry point (see my firsthand review of The Ordinary). Biossance is the more premium, more hydrating experience, and for me it delivered more. For how these serums stack up on price per ml and label transparency, see my master copper peptide comparison.

Would I repurchase?

I am about halfway through my bottle and I have been happy enough that I would consider it a keeper in my routine. Of the ones I have used firsthand, this is my favorite so far.

Who it is for

• People who want a more premium, hydrating copper peptide serum and do not mind paying for it
• Normal-to-dry skin that benefits from a squalane base
• Men who want one serum that makes skin feel hydrated and healthy without a greasy finish

Who might skip it: very oily skin, or anyone who just wants the cheapest way to test copper peptides first.

Bottom line

After two and a half months of twice-daily use, Biossance Squalane + Copper Peptide is the copper peptide serum I have gotten the most out of personally: immediate plumped hydration, smoother texture within a few weeks, and over time the look of softer fine lines, with a premium feel and no off smell. The price, and the fact that the brand does not disclose its copper concentration, are the main trade-offs. For me, it earned its place in my routine.

A note on how I review: this is a product I actually bought and use daily, so these impressions are genuinely mine. Where I reference products I have not personally tested, I rely on published labels and sourced analysis and I say so. See my how we research page.